Medicine

Science of the Fifth Sense

Imagine my frustration while trying to bottle-feed breast milk to my 4-week-old baby. The little guy was not happy taking his nature-made meal from a bottle, even if they had different-styled nipples. He would only take the breast milk directly from his mom.  As a result, I wasted no time raising this concern with his

microsporidia harpooning a cell

Microsporidia: tiny parasites with big impacts

A vessel is harpooned and infiltrated by an enemy, then robbed of its precious cargo – this imagery may call to mind Long John Silver or other fictional marauders, but these events happen every day, all around us, on a scale so small we cannot see it. I'm referring to microsporidia, a group of real-life,

Toxicology and Poisons: a Cat and Mouse Game

Murder is as old as mankind. Or so the saying goes. Every culture has a history of poisons, from the ironically named “elixirs of life” eagerly sought after by early Chinese emperors and nobles, to the Poison Damsels (Visha Kanya) of ancient Indian mythology that could kill you with just a drop of the deadly

The Future of CRISPR Therapy

Although rewriting the code of life seems like a daunting task, scientists have managed to do just that. You've probably heard of CRISPR technology, a burgeoning genetic tool that has seen use in a multitude of applications, from treating Duchenne muscular dystrophy in mice to making crops more sustainable. The technology offers a method of

The Fault in Our Epigenome: The science behind aging

From the Yoruba tradition of throwing cowrie shells, to the Roma fortune tellers peering at palms, people throughout history have wondered if there was some sort of physical or external way to map out the path of our lives. Modern day scientists are still pondering how to predict the future, but instead of looking up

mitochondial DNA is inherited from the mother, versus nuclear DNA which comes from both parents

What your mama (mostly) gave you

Anyone who knows me knows that mitochondria are pretty much my life. My Ph.D. focuses on making these little cellular power plants more efficient at producing energy so that they can help muscles heal faster after traumatic injury. More than that, though, I want to teach people that mitochondria are more than just “the powerhouse

Diving into the Homo-Delphinus connection

Humans have shared a special bond with a certain animal since the time of Aristotle. Artworks as early as 1500 BC depicted interactions with this fascinating creature. Members of this species have assisted the US Navy, and have also been used as therapy animals for patients with Down syndrome and autism.  These amiable beings are

Psychedelics: from poison to antidote

The term psychedelics, or hallucinogens, describes a class of drugs that produce significantly altered perception when ingested. Due to their ability to cause lasting effects on a user's mood and thought, some researchers believe they have therapeutic potential for treating difficult mental illnesses like depression, addiction, PTSD, and Alzheimer's, though only a few institutions currently

The False Promise of Animal Testing Part 2: Human Organs, Simplified

If we accept the idea that animal models are holding back drug development due to a potential inability to predict safety and efficacy in humans, what can be done to fix it? Increasingly, scientists are using human cells cultured in vitro to assess the safety and efficacy of new drug compounds. While in vitro cell

The False Promise of Animal Testing: Safety and Efficacy

One fact that was drilled into my head while studying biomedical science was how few experimental drugs ever make it past clinical trials. A failure rate of 90% is reported. This struck me as odd, but I chalked it up as an example of how difficult drug development is and didn't ask why. That changed

Rethinking Anorexia: Making the Biopsychosocial Connection

With only 50% of patients recovering fully in the long-term, anorexia is the deadliest psychiatric disorder. Typically associated with poor body-image and unhealthy eating habits, anorexia has captivated and bewildered the minds of laymen and scientists alike. While not every person suffering from anorexia is underweight,  there is still a general misunderstanding of what is

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